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ESETT (Established Status Epilepticus Treatment Trial) is a seizure study taking place at the University of Maryland Medical Center that may affect you or someone you know. A prolonged seizure affects individuals of all ages, from the very young to the elderly.

Status epilepticus (SE) is seizure activity that does not stop. Patients with SE are given a drug like valium to make their seizures stop. Seizures that continue after the first dose of treatment is given are known as established status epilepticus (ESE).

ESETT is a research study designed to find out which of three commonly used drugs best stops ESE.

Normally, researchers get permission before a person can be included in a study. A person having a seizure will not be able to give consent. Since a seizure that will not stop on its own must be treated quickly, there will not be enough time to locate and talk to the person’s legal representative about the study, so the person will be enrolled in the study without his/her legal representative’s consent. This is called Exception from Informed Consent (EFIC).

The study is currently closed for recruitment and results will be released soon.