Venous thromboembolism effects between 300 -600 patients in the US per year. Pulmonary embolism is the 3rd leading cause of cardiovascular death in the US and approximately 10% of pulmonary embolisms are rapidly fatal. In this recorded Grand Rounds presentation, Dr. Rafael Cires-Drouet, assistant professor of medicine at the University of Maryland School of Medicine and medical director of the Wound Healing Center and Pulmonary Embolism Response Team at the University of Maryland Medical Center, discusses the management of Pulmonary Embolism.