Liver and Gallbladder Cancer

Malignancies confined to the liver are one of the most common forms of cancer. There are two basic types of the disease: primary liver cancer originates in the tissues of the liver itself, while metastatic liver cancer occurs when cancer cells spread from other parts of the body, most commonly from the stomach, pancreas, breast or lung. Ultimately, about a third of all cancers will spread to the liver.

Surgery usually provides the best chance for a cure, and our surgical specialists are among the best in the country. In some cases, however, tumors develop internally within the liver and complete surgical removal is not possible.

The University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center (UMGCCC) offers a comprehensive Liver-Directed Therapies Program, providing the most advanced treatments available -- from complete or partial surgical removal to systemic, combination therapies to regional, targeted treatment options -- to provide the very best outcomes possible for patients with all forms of liver cancer.

Our multidisciplinary Liver-Directed Therapies Program team consists of experts in medical oncology, radiation oncology, surgical oncology, interventional radiology, nuclear medicine, gastroenterology, hepatology and pathology. These specialists meet and consult weekly to develop the best plan of treatment for each individual patient.

Some of the advanced therapies offered in our Liver-Directed Therapies Program include:

Selective Internal Radiation Therapy (SIRT)

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Selective Internal Radiation Therapy (SIRT) is a type of internal radiation therapy that uses millions of microscopic beads injected into the liver, directly to the site of the tumor. UMGCCC is one of the select few state-of-the-art facilities that provide this treatment in the United States. Our team of experts has one of the largest experiences in the United States treating patients with Yttrium-90 microspheres (SIR-Spheres) for inoperable liver cancer. To date, we have treated more than 140 patients with SIRT, and our experts have presented the results of our SIRT research and treatment at both national and international meetings.