The STC at UMMC specializes in complex, multi-system adult trauma and provides care to over 8,025 patients per year. Referrals for admission come from Maryland and its surrounding states.

Eighteen percent of the patients are flown in by medevac helicopter, and the remainder arrive by ambulance. Half of the patient population admitted to the STC at UMMC is characterized as "risk takers," and their admissions are related to high-risk behaviors including: alcohol and/or drug abuse, reckless driving, speeding, and violence.

The SMART (Saving Maryland At Risk Teens) program was developed by trauma nurses at the STC at UMMC in 1979 in response to a nursing department goal, "to prevent trauma in the state of Maryland."