William F. Regine, MD, FACR, FACRO

  • Isadore and Fannie Schneider Foxman Chair and Professor of Radiation Oncology

  • President, University of Maryland Medical Center Staff Organization

  • Executive Director, Maryland Proton Treatment Center (MPTC)

William F. Regine, MD, FACR, FACRO


  • Head and Neck Radiation Oncology

  • Neurologic Radiation Oncology

  • Sarcoma and Connective Tissue Radiation Oncology

  • Gastrointestinal Radiation Oncology

  • Radiation Oncology

Available for Telemedicine Visits

About William F. Regine, MD, FACR, FACRO

Toggle accordion item

Dr. Regine is the Isadore and Fannie Schneider Foxman Chairman and Professor of Radiation Oncology at the University of Maryland ranked top 5 in the country in NIH rankings.

His areas of interest include:

  • Gastrointestinal Malignancies including Pancreatic Cancer
  • Central Nervous System Malignancies including Brain Metastases
  • Stereotactic Body Radiation Therapy (SBRT)
  • Gamma Knife (Radiosurgery)

A graduate of the of the State University Health and Science School of Medicine in Syracuse NY, Dr. Regine obtained his training at Thomas Jefferson University Hospital in Philadelphia where he also completed a Radiation Oncology Fellowship in Gastrointestinal and Head and Neck malignancies (inclusive of training at the University of Florida).

Dr. Regine is considered a national and international expert in the area of GI and CNS malignancies, as well as in the use of Stereotactic Radiosurgery. His first faculty appointment was at St. Jude's Children's Cancer Research Hospital where as a Clinical Investigator he helped redefined new standards of care in children with rhabdomyosarcomas. After 2 years at St. Jude's he dedicated his career to clinical research in adult cancer patients.

Dr. Regine has served as Principal Investigator or Co-Principal Investigator in at least 4 national NCI sponsored cooperative group clinical trials. He served as the Principal Investigator/Study Chairman of the U.S. Intergroup/ NRG Oncology 9704 study evaluating adjuvant therapy in patients with pancreatic cancer published in the Journal of the American Medical Association (JAMA). This study defined a new standard of care for patients with pancreatic cancer. He has also been the Radiation Oncology Principal Investigator/Study Chairman of at least 2 additional Institutional clinical trials published in JAMA and the Lancet which defined new standards of care for patients with brain metastases and malignant spinal cord compression. He is co-editor "Principles and Practices of Stereotactic Radiosurgery," the first comprehensive textbook of its kind. In addition, he is also a member of the GI and Brain Tumor steering committees for the NRG Oncology and was the Chairman of the GI section of the National Oral Board examination for trainees in Radiation Oncology.

Dr. Regine was named a "Top Doctor" in the specialty of Radiation Oncology by Baltimore Magazine and "Super Doctor" in Mid-Atlantic by Washington Post Magazine multiple years. In 2016, he was given the Entrepreneur of the Year Award by the University of Maryland Baltimore and in 2018, he was elected President of the University of Maryland Medical Center Medical Staff Organization.

Related Video:

Gender: Male

Language(s): English


  • UM Upper Chesapeake Health

  • UM Baltimore Washington Medical Center

  • University of Maryland Medical Center

  • Member of UM Faculty Physicians, Inc.

How to Schedule a Telemedicine Visit

In case of emergency, please call 911

University of Maryland Radiation Oncology Associates, PA

22 South Greene Street
Gudelsky Basement
Suite GGK0107
Baltimore, MD 21201
Get Directions

PH: 410-328-6080

PH: 410-328-6080

FAX: 410-328-6911

Maryland Proton Treatment Center

850 West Baltimore Street
Baltimore, MD 21201
Get Directions

PH: 410-369-5200

PH: 410-369-5200

FAX: 410-347-0870