COVID-19: Pfizer-BioNTech Vaccine
Developed by American pharmaceutical company Pfizer and German firm BioNTech, this COVID-19 vaccine was authorized for emergency use by the U. S. Food and Drug Administration on December 11, 2020. The Pfizer vaccine was the first COVID-19 vaccine made available in the United States. On May 10, 2021, the FDA approved the expansion of the emergency use authorization to include children ages 12 to 15.
Important Information about the Pfizer Vaccine
- Number of doses required: 2 doses of the same vaccine
- Time between doses: Minimum of 21 days
- Authorized for: People age 12 and up
- Time to reach full protection: 14 days after second dose
- Effectiveness: Nearly 100% effective in preventing hospitalization and death
- How long protection will last: Unknown at this time; studies are ongoing
- Storage: Ultracold temperature as low as -112 degrees Fahrenheit
How the Pfizer Vaccine Works
Both the Pfizer and Moderna COVID-19 vaccines are based on messenger RNA (mRNA) technology. mRNA vaccines contain a code that provides the cells "instructions" to create antibodies to protect against COVID-19. Learn more about how mRNA vaccines work.
This type of vaccine does not contain any part of the virus, so it cannot cause COVID-19.
Who Can and Cannot Get the Pfizer Vaccine
The vast majority of people will be able to get the Pfizer vaccine or any of the other approved vaccines when it's their turn and they are eligible. However, a few groups of people cannot receive it or should consult a doctor first.
- Children under the age of 12 are not eligible to receive the Pfizer vaccine at this time; studies are underway to test its safety and effectiveness in children.
- Pregnant women, as well as those who are breastfeeding or may become pregnant, may receive the Pfizer vaccine. However, they should talk to their doctor first because clinical testing in this group has not been completed.
- People who allergic to any of its ingredients or had an allergic reaction to their first dose cannot receive this vaccine. Please see additional information about allergic reactions below.
How the Pfizer Vaccine Was Developed
Although the vaccine was developed in less than a year, they went through the same rigorous approval process as laid out by the FDA. No safety steps were skipped. Learn more about the vaccines' development and approval process.
In May 2020, the University of Maryland School of Medicine (UMSOM) became the first in the United States to begin testing this COVID-19 vaccine candidate. Learn more about how we're fighting COVID at the University of Maryland Medical System.
Allergic Reactions and Side Effects
Please see the FDA's Fact Sheet for the Pfizer vaccine or the most up-to-date information on:
- Vaccine ingredients
- Side effects and what to do about them
- Possible allergic reactions
If you have a history of immediate or severe allergic reaction to anything – especially another vaccine or injectable medicine – it is strongly recommended you talk to your doctor before getting the vaccine. This is so your doctor can confirm it is safe for you to get the vaccine.
If you have a history of severe allergic reactions, you will also be monitored for 30 minutes after your vaccination.
Before you get vaccinated, you should talk to your doctor if you:
- Have any allergies
- Have a fever
- Have a bleeding disorder or are on a blood thinner
- Are immunocompromised or are taking a medicine that affects your immune system
- Are pregnant or plan to become pregnant
- Are breastfeeding
- Have received another COVID-19 vaccine
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