COVID-19: Moderna Vaccine
Developed by Massachusetts-based biotechnology company Moderna Therapeutics, this COVID-19 vaccine was authorized for emergency use by the U.S. Food and Drug Administration on December 18, 2020.
Important Information about the Moderna Vaccine
- Number of doses required: 2 doses of the same vaccine
- Time between dose: Minimum of 28 days
- Authorized for: People age 18 and up
- Time to reach full protection: 14 days after second dose
- Effectiveness: Nearly 100% effective in preventing hospitalization and death
- How long protection will last: Unknown at this time; studies are ongoing
- Storage: Freezer (-13 to 5 degrees Fahrenheit)
How the Moderna Vaccine Works
Both the Moderna and Pfizer COVID vaccines are based on messenger RNA (mRNA) technology. mRNA vaccines contain a code that provides the cells "instructions" to create antibodies to protect against COVID-19. Learn more about how mRNA vaccines work.
This type of vaccine does not contain any part of the virus, so it cannot cause COVID-19.
Who Can and Cannot Get the Moderna Vaccine
The vast majority of people will be able to get the Moderna vaccine or any of the other approved vaccines when it's their turn and they are eligible. However, a few groups of people cannot receive the vaccine or should talk to a doctor first.
- Children under the age of 18 are not eligible to receive the Moderna vaccine at this time; studies are under way to test its safety and effectiveness in children.
- Pregnant women, as well as those who are breastfeeding or may become pregnant, may receive the Moderna vaccine. However, they should talk to their doctor first because clinical testing in this group has not been completed.
- People who are allergic to any of the vaccine's ingredients or those who had an allergic reaction to their first dose cannot receive this vaccine. Please see additional information about allergic reactions below.
How the Moderna Vaccine Was Developed
Although the Moderna vaccine was developed quickly, it still underwent the same rigorous approval process as laid out by the FDA. No safety steps were skipped. Learn more about the vaccines' development and approval process.
In September 2020, University of Maryland School of Medicine became one of the clinical research sites working on phase three testing of this vaccine. A key focus of this trial was to include people most impacted by COVID-19, including those from the African American and Latino communities. Learn more about how we're fighting COVID at the University of Maryland Medical System.
Side Effects of the Moderna Vaccine
Possible side effects, which usually go away within 24-48 hours after receiving the vaccine, include:
Reactions at the injection site, including:
- Swelling (hardness)
- Tenderness and swelling of the lymph nodes in the same arm of the injection
General side effects:
- Muscle and/or joint pain
- Nausea and vomiting
Possible Allergic Reactions to the Moderna Vaccine
While severe allergic reactions have been extremely rare, there is a slight risk of an allergic reaction to the Moderna vaccine. Signs of an allergic reaction may include:
- Difficulty breathing
- Swelling of your face and throat
- A fast heartbeat
- A bad rash all over your body
- Dizziness and weakness
Any immediate allergic reaction to another vaccine or injectable medicine, no matter how severe, is considered a precaution by the Centers for Disease Control and Prevention (CDC). In other words, you may be at higher risk of having a reaction to the vaccine.
If you have a history of immediate or severe allergic reaction to anything – especially another vaccine or injectable medicine – it is strongly recommended you talk to your doctor before getting the vaccine. This is so your doctor can confirm it is safe for you to get the vaccine.
If you have a history of severe allergic reactions, you will also be monitored for 30 minutes after your vaccination.
If you have a severe allergic reaction to the first dose of this vaccine, you should not receive the second dose. If you are allergic to any ingredient of the vaccine, you should not receive the vaccine.
Please see the Food and Drug Administration EUA Fact Sheet for information on vaccine ingredients for Moderna.
The vaccine does not contain any egg-based technology, so there is no concern for people with egg allergies like there may be with other vaccines.
Before you get vaccinated, you should talk to your doctor if you:
- Have any allergies (see additional information above)
- Have a fever
- Have a bleeding disorder or are on a blood thinner
- Are immunocompromised or are taking a medicine that affects your immune system
- Are pregnant or plan to become pregnant
- Are breastfeeding
- Have received another COVID-19 vaccine
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